Research Question Examples: 50+ Strong Research Questions Across Disciplines
A strong research question is the spine of any research project. It defines what the study is asking, what data you'll need, and what kind of answer would count as a finding. This article collects more than 50 fully-operationalized research question examples across the major disciplines, methodological approaches, and project types. Each example is written as a real research question someone could actually study, with the population, variables, comparison, outcome, and time frame specified rather than left vague. For step-by-step guidance on developing your own research question from a broad topic, including the FINER, PICO, PICOT, and SPIDER frameworks, see our companion article on how to write a research question.
Use the examples below as models for your own work. The structure of each example, with its specified population, defined variables, and clear outcome measure, is more important than the specific topic. The same structural pattern works whether you're studying social media use among adolescents, treatment effects in adults with diabetes, or the development of a literary genre across decades. The examples are organized first by methodological approach (quantitative, qualitative, mixed-methods), then by framework (PICO/PICOT, SPIDER), then by project type (undergraduate, master's, doctoral, grant), and finally by side-by-side weak versus strong comparisons that show the same topic developed at two different levels of specificity.
What Makes a Strong Research Question?
Before reviewing examples, it helps to know what to look for. A strong research question is focused on a single problem, specific in its terms and variables, researchable using established methods, feasible within your project's resources, complex enough to merit sustained investigation, and relevant to your field. The examples below all meet these criteria. Vague topic descriptions like "the effects of social media" are not research questions; specific, operationalized inquiries like "Does daily duration of TikTok use predict depression symptoms among US adolescents aged 13 to 17, controlling for prior depression history and offline social engagement?" are.
For full coverage of the FINER, PICO, PICOT, and SPIDER frameworks and the eight-step process for developing a research question from a broad topic, see our how to write a research question guide.
Research Questions in Quantitative Studies
Quantitative research questions ask about measurable variables, relationships, and effects. They use language like "how many," "to what extent," "is there a relationship between," "does X predict Y," and "what is the difference between." Quantitative questions imply statistical analysis and produce numerical estimates with associated uncertainty. The examples below are fully operationalized: each has a defined population, a measurable outcome, and a specified relationship being tested.
Quantitative research question examples in the social sciences and economics
- Among married couples in the United States, do husbands and wives differ in financial risk tolerance, as measured by the standard financial risk tolerance scale, after controlling for income, education, and age? (Comparative; this is the question addressed in Fisher and Yao's 2017 study using nationally representative US data.)
- Does each additional year of post-secondary education increase lifetime earnings among US workers aged 25 to 64, after controlling for cognitive ability, family background, and field of study? (Predictive)
- Among first-generation college students at large public universities, does participation in a structured first-year learning community increase four-year graduation rates compared to non-participation, with student characteristics balanced through propensity score matching? (Causal, quasi-experimental)
- Does an increase in the federal Earned Income Tax Credit reduce poverty rates among childless adult workers in the United States, as measured by the Supplemental Poverty Measure, in the year following the policy change? (Evaluative, causal)
- What is the relationship between household financial literacy scores and retirement savings adequacy among US households aged 45 to 64, as measured by the Survey of Consumer Finances? (Correlational)
Quantitative research question examples in the health and biomedical sciences
- Among adults aged 65 and older with type 2 diabetes, does twelve weeks of supervised resistance training, three sessions per week, reduce HbA1c at 12 weeks and 6 months post-intervention compared to standard care alone? (PICOT, randomized controlled trial)
- What proportion of US adults aged 18 to 64 received a diagnosis of major depressive disorder in 2024, and how does prevalence vary by age, sex, race/ethnicity, and household income? (Descriptive epidemiological)
- Does daily duration of social media use predict depression symptom severity, as measured by the PHQ-9, among US adolescents aged 13 to 17, controlling for prior depression history and offline social engagement? (Correlational)
- Among patients with stage III colon cancer, does the addition of an immune checkpoint inhibitor to standard FOLFOX chemotherapy improve five-year overall survival compared to FOLFOX alone? (PICOT, comparative effectiveness)
- What is the dose-response relationship between weekly minutes of moderate-to-vigorous physical activity and all-cause mortality among US adults aged 40 and older, after adjusting for age, sex, BMI, and baseline health status? (Correlational)
Quantitative research question examples in education research
- Does universal pre-K enrollment increase third-grade reading proficiency among children from low-income households, as measured by state standardized assessments, compared to children who did not attend pre-K, in school districts that adopted universal pre-K between 2018 and 2022? (Causal, quasi-experimental)
- What is the relationship between average class size and standardized math test scores in US public elementary schools, controlling for school-level socioeconomic status and teacher experience? (Correlational)
- Does the use of intelligent tutoring systems in middle school algebra produce greater learning gains than teacher-led instruction alone, as measured by end-of-year algebra assessments, in a randomized trial across 50 US middle schools? (Causal, RCT)
- How does the four-year graduation rate of first-generation college students differ from that of continuing-generation students at large public research universities, after controlling for high school GPA, SAT/ACT scores, and high school socioeconomic status? (Comparative)
Quantitative research question examples in engineering and computer science
- Does a transformer-based language model with 7 billion parameters, fine-tuned on a corpus of 100,000 legal contracts, outperform a 70-billion-parameter general-purpose model on a benchmark of 500 contract clause classification tasks, as measured by macro-averaged F1 score? (Comparative, computational)
- What is the relationship between the carbon fiber volume fraction and the tensile strength of carbon-fiber-reinforced polymer composites, across volume fractions from 30 to 70 percent, at room temperature? (Correlational, materials science)
- Does the addition of a battery energy storage system to a 50-megawatt solar photovoltaic plant reduce annual curtailment by at least 20 percent, as estimated through hourly production modeling using 10 years of regional solar irradiance and demand data? (Predictive, energy systems)
- How does the throughput of a 5G millimeter-wave network compare to that of sub-6 GHz 5G in dense urban environments, measured at distances of 100, 250, and 500 meters from the base station under line-of-sight and non-line-of-sight conditions? (Comparative, telecommunications)
Quantitative research question examples in the natural sciences
- What is the relationship between sea surface temperature anomalies in the eastern equatorial Pacific and winter precipitation in the southwestern United States, based on historical records from 1950 to 2024? (Correlational, climatology)
- Does CRISPR-Cas9 knockout of the BRCA1 gene in human breast epithelial cell lines increase the rate of double-strand DNA breaks following ionizing radiation exposure, compared to wild-type controls? (Causal, molecular biology)
- How does the photoluminescence quantum yield of CsPbI3 perovskite nanocrystals vary with crystal size between 5 and 20 nanometers, at room temperature in oxygen-free conditions? (Descriptive/correlational, materials chemistry)
- What is the population structure of Atlantic cod (Gadus morhua) in the Northwest Atlantic, based on whole-genome SNP data from 500 individuals collected across the Gulf of Maine, Georges Bank, and the Scotian Shelf? (Descriptive, population genetics)
Research Questions in Qualitative Studies
Qualitative research questions ask about experiences, meanings, processes, and contexts. They use language like "how do," "what is the experience of," "how do participants describe," and "in what ways." Qualitative questions imply interview, observation, focus group, or document analysis methods, and they produce rich descriptions, theoretical insights, and conceptual frameworks rather than numerical estimates.
Qualitative research question examples in the social sciences
- How do first-generation college students at large public research universities describe their experience of belonging on campus during their first year, and how do these descriptions differ from those of continuing-generation students? (Phenomenological)
- How do adult children of immigrants in the United States navigate competing cultural expectations around career, marriage, and family, and how do these negotiations evolve across the life course? (Narrative inquiry)
- What strategies do small business owners in underserved Appalachian communities in western Pennsylvania use to access capital, and how do they describe the barriers and supports they encounter in the process? (Grounded theory)
- How do families in rural West Virginia talk about the opioid epidemic in their communities, and how do they describe its effects on family relationships across three generations? (Ethnographic interview)
Qualitative research question examples in nursing and health sciences
- How do patients with stage IV cancer describe their decision-making process when considering enrollment in early-phase clinical trials, and what factors do they weigh in their decisions? (Phenomenological)
- What are the lived experiences of registered nurses providing end-of-life care in pediatric intensive care units, and how do they describe the emotional and professional supports they need? (Phenomenological, SPIDER framework)
- How do family caregivers of older adults with advanced dementia describe their changing roles and identities over the course of providing care, from initial diagnosis through end-of-life? (Narrative inquiry)
- How do adolescents with type 1 diabetes describe their decision-making about disclosure of their condition to peers, romantic partners, and employers, and how do these decisions change as they transition into early adulthood? (Grounded theory)
Qualitative research question examples in education
- How do new teachers in their first three years of teaching describe the gap between their teacher preparation programs and the realities of their classrooms, and what supports do they identify as most useful in bridging that gap? (Grounded theory)
- How do high school students in rural communities describe their college decision-making process, and what role do family, peers, school counselors, and online information sources play in their decisions? (Phenomenological)
- How do teachers describe the integration of generative AI tools into their classroom practice during the 2024 to 2026 school years, and what tensions and possibilities do they identify? (Case study)
Qualitative research question examples in the humanities
- How do Appalachian women writers from 1970 to 2010 represent the relationship between place and identity in their fiction, and how do these representations change across the period in response to the region's economic transitions? (Literary analysis with thematic coding)
- How does Aristotle's account of moral responsibility in the Nicomachean Ethics differ from the Kantian account, and which conception better accommodates the moral significance of luck? (Philosophical analysis)
- How does the representation of Black mothers in twentieth-century American literature evolve from the Harlem Renaissance through the post-civil-rights era, and what literary techniques do authors use to construct these representations? (Literary analysis)
Research Questions in Mixed-Methods Studies
Mixed-methods research uses both quantitative and qualitative approaches in the same study, often with separate questions for each component or a primary question with a single integrated framework. The examples below show how mixed-methods questions are typically structured, with a quantitative component, a qualitative component, and an integration question.
- Mixed-methods study of college student belonging. Quantitative: How does the four-year graduation rate of first-generation college students differ from continuing-generation students at large public universities? Qualitative: How do first-generation students describe their experience of belonging on campus during their first year? Integration: To what extent do quantitative differences in graduation outcomes correspond to qualitative differences in students' descriptions of their belonging experiences?
- Mixed-methods evaluation of a community health intervention. Quantitative: Does a community health worker home visit program reduce 30-day hospital readmission rates among adults with congestive heart failure compared to standard discharge protocols? Qualitative: How do patients and community health workers describe the relationship that develops over the course of the home visits? Integration: How do the relational dynamics described qualitatively help explain the magnitude and direction of the quantitative effect?
- Mixed-methods study of small business adaptation. Quantitative: What proportion of small businesses in underserved Appalachian counties received Paycheck Protection Program funding during 2020 to 2021, and how did receipt vary by business size, sector, and owner demographics? Qualitative: How do small business owners describe the experience of applying for and using the funding? Integration: How do qualitative descriptions of barriers help explain quantitative patterns of unequal access?
Research Questions Using PICO and PICOT Frameworks
PICO and PICOT are the standard frameworks for clinical research questions in medicine, nursing, public health, and the health sciences. PICO stands for Population, Intervention, Comparison, and Outcome; PICOT adds Time as a fifth element. The examples below break each question into its PICO/PICOT components to make the framework explicit.
PICOT research question examples in clinical medicine
- P: Adults aged 65 and older with type 2 diabetes; I: twelve weeks of supervised resistance training, three sessions per week; C: standard care alone; O: HbA1c reduction; T: 12 weeks and 6 months post-intervention. Full question: "Among adults aged 65 and older with type 2 diabetes, does twelve weeks of supervised resistance training compared to standard care alone reduce HbA1c at 12 weeks and 6 months post-intervention?"
- P: Patients with stage III colon cancer following surgical resection; I: standard FOLFOX chemotherapy plus an immune checkpoint inhibitor; C: standard FOLFOX chemotherapy alone; O: overall survival; T: at five years post-randomization. Full question: "Among patients with stage III colon cancer following surgical resection, does the addition of an immune checkpoint inhibitor to standard FOLFOX chemotherapy improve five-year overall survival compared to FOLFOX alone?"
- P: Pregnant women in the third trimester with gestational hypertension; I: low-dose aspirin (81 mg daily); C: placebo; O: incidence of preeclampsia; T: through delivery. Full question: "Among pregnant women in the third trimester with gestational hypertension, does daily low-dose aspirin compared to placebo reduce the incidence of preeclampsia through delivery?"
PICOT research question examples in nursing
- P: Adult patients in medical-surgical units; I: hourly nursing rounds; C: standard nursing assessment frequency; O: patient call light frequency and inpatient fall rates; T: over a six-month period. Full question: "Among adult patients in medical-surgical units, does hourly nursing rounding compared to standard assessment frequency reduce patient call light frequency and inpatient fall rates over a six-month period?"
- P: Hospitalized adults aged 65 and older at risk of pressure ulcers; I: use of a standardized pressure ulcer prevention bundle; C: usual care; O: incidence of stage 2 or higher pressure ulcers; T: during the hospitalization. Full question: "Among hospitalized adults aged 65 and older at risk of pressure ulcers, does implementation of a standardized pressure ulcer prevention bundle compared to usual care reduce the incidence of stage 2 or higher pressure ulcers during the hospitalization?"
PICOT research question examples in public health
- P: Adults aged 18 to 64 in low-income urban neighborhoods; I: a community-based smoking cessation program with text-message support; C: standard cessation counseling alone; O: seven-day point prevalence smoking abstinence; T: at six months post-enrollment. Full question: "Among adults aged 18 to 64 in low-income urban neighborhoods, does a community-based smoking cessation program with text-message support compared to standard cessation counseling alone increase seven-day point prevalence smoking abstinence at six months post-enrollment?"
Research Questions Using the SPIDER Framework
The SPIDER framework was developed for qualitative and mixed-methods research where PICO doesn't fit. SPIDER stands for Sample, Phenomenon of Interest, Design, Evaluation, and Research type. The examples below break each question into its SPIDER components.
- S: Patients with stage IV cancer enrolled at a National Cancer Institute-designated comprehensive cancer center; PI: decision-making about enrollment in early-phase clinical trials; D: in-depth semi-structured interviews; E: participants' descriptions of factors weighed in their decisions; R: qualitative phenomenological. Full question: "How do patients with stage IV cancer enrolled at NCI-designated cancer centers describe their decision-making process when considering early-phase clinical trial enrollment, and what factors do they weigh?"
- S: Registered nurses with at least two years of experience in pediatric intensive care units; PI: the lived experience of providing end-of-life care; D: longitudinal in-depth interviews conducted three times over a six-month period; E: nurses' descriptions of emotional and professional supports needed; R: qualitative phenomenological. Full question: "What are the lived experiences of pediatric ICU registered nurses providing end-of-life care, and how do they describe the supports they need?"
- S: First-generation college students at large public research universities; PI: the experience of belonging on campus during the first year; D: focus groups conducted in fall, winter, and spring of the first year; E: students' descriptions of belonging and how those descriptions evolve across the year; R: qualitative longitudinal. Full question: "How do first-generation college students at large public universities describe their experience of belonging on campus across their first year?"
Research Question Examples by Project Type
The form of a research question depends on the project it's framing. The examples below show questions appropriate to four common project types: undergraduate research papers, master's theses, doctoral dissertations, and grant applications.
Research question examples for undergraduate research papers
Undergraduate questions should be narrow enough to answer with secondary sources or modest primary data within a semester. Strong undergraduate questions are focused, specific, and feasible for the page length.
- How did US monetary policy respond to the inflation surge of 2021 to 2023, and how did this response differ from the Federal Reserve's response to inflation in the late 1970s and early 1980s? (Comparative historical analysis)
- What are the major arguments for and against universal basic income presented in the academic economics literature from 2015 to 2025, and how do these arguments differ between proponents and critics? (Literature review)
- How do three contemporary novels set in Appalachia (Ron Rash's Serena, Barbara Kingsolver's Demon Copperhead, and Silas House's Southernmost) represent the relationship between extractive industries and community identity? (Literary analysis)
Research question examples for master's theses
Master's thesis questions are typically answerable with primary or secondary data within a 12 to 24 month timeline, with one main question and possibly two or three sub-questions.
- Main: Does participation in a high school financial literacy course increase financial decision-making quality among graduates two years after high school, as measured by a financial decision-making assessment? Sub-question 1: Do effects differ by household income background? Sub-question 2: Do effects persist or fade over the two-year follow-up period?
- Main: What is the relationship between social media use intensity and academic performance among undergraduate students at one large public university, measured by self-reported daily screen time and term GPA? Sub-question: Does this relationship differ by major?
- Main: How do healthcare workers at a single large urban hospital describe their experience of moral distress during the post-acute phase of the COVID-19 pandemic from 2022 to 2024? Sub-question: How do these descriptions differ between physicians, nurses, and respiratory therapists?
Research question examples for doctoral dissertations
Doctoral questions should be sophisticated enough to merit four to six years of training and should make a clear contribution to the field. Many dissertations now use the three-paper format, with each paper having its own research question.
- Three-paper dissertation on household financial decision-making. Paper 1: Are there gender differences in financial risk tolerance among married US couples, controlling for income, education, and age? Paper 2: Do gender differences in risk tolerance translate into differences in household investment portfolio allocations, using linked spousal survey data? Paper 3: How do married couples describe the process of making joint financial decisions, and how do gendered differences in stated risk tolerance manifest in actual joint decision-making conversations?
- Single-question dissertation on educational policy. Does universal pre-K enrollment increase third-grade reading proficiency, fourth-grade math proficiency, and high school graduation rates among children from low-income households, in school districts that adopted universal pre-K between 2010 and 2015, with effects estimated through a difference-in-differences design comparing adopting and non-adopting districts?
- Three-paper dissertation in biomedical research. Paper 1: What is the genetic landscape of treatment resistance in EGFR-mutant non-small cell lung cancer, based on whole-exome sequencing of 200 paired pre-treatment and post-progression tumor samples? Paper 2: Does a novel third-generation EGFR inhibitor combined with a MET inhibitor overcome resistance in patient-derived xenograft models of EGFR-mutant NSCLC with MET amplification? Paper 3: What is the safety, tolerability, and preliminary efficacy of the combination in a phase I dose-escalation trial in patients with EGFR-mutant NSCLC and MET amplification who have progressed on standard EGFR inhibitor therapy?
Research question examples for grant applications
Grant applications, including NIH R01s, NSF proposals, and ERC grants, typically have specific aims that function as research questions. The aims should collectively justify the funding request and demonstrate the team can answer them.
- NIH R01 on cardiovascular health (three specific aims). Aim 1: Determine whether long-term exposure to fine particulate matter (PM2.5) increases the incidence of myocardial infarction in a cohort of 50,000 US adults aged 45 to 75, followed for 10 years, after adjustment for known cardiovascular risk factors. Aim 2: Identify the molecular mechanisms by which PM2.5 exposure promotes atherosclerotic plaque instability, using ApoE-knockout mouse models. Aim 3: Test whether a community-level air quality intervention reduces inflammatory biomarker levels among adults living within one mile of major freeways, using a stepped-wedge design across six study sites.
- NSF proposal in computer science (two specific aims). Aim 1: Develop a novel algorithm for verifying the safety of neural network controllers in autonomous vehicles, with formal guarantees on collision avoidance under bounded perturbations. Aim 2: Empirically evaluate the algorithm on a benchmark of 10 standard autonomous driving scenarios, comparing it to four existing verification approaches on metrics of completeness, soundness, and computational efficiency.
- ERC Starting Grant in economics (single research question across three sub-aims). Main question: How do household financial decisions respond to large, unexpected wealth shocks, and through what mechanisms do these responses unfold? Sub-aim 1: Estimate the consumption response to lottery winnings in administrative tax data from a Northern European country with universal lottery participation. Sub-aim 2: Estimate the labor supply response and decompose it into hours, occupation switching, and retirement margins. Sub-aim 3: Identify the role of financial advice access in shaping the response, using a quasi-experimental variation in advisor availability.
Weak vs Strong Research Question Examples
The clearest way to learn what makes a strong research question is to compare a weak version to a strong version of the same topic. The weak versions below all describe topics rather than specifying questions; the strong versions specify the population, the relationship, the outcome, and the conditions. The same topic can almost always be sharpened into a strong research question through these specifications.
Example 1: Social media and mental health
Weak: How does social media affect mental health?
Why it's weak: "Social media" and "mental health" are both umbrella terms covering hundreds of platforms and dozens of clinical and subclinical conditions. "Affect" doesn't specify direction, magnitude, or mechanism. The question is unanswerable as written.
Strong: Does daily duration of TikTok use predict depression symptom severity, as measured by the PHQ-9, among US adolescents aged 13 to 17, controlling for prior depression history and offline social engagement, in a longitudinal sample followed across the 2024 to 2025 academic year?
Why it's strong: The platform is specified (TikTok). The variable is operationalized (daily duration). The outcome is measured (PHQ-9). The population is defined (US adolescents 13 to 17). Confounders are addressed. The time frame is set.
Example 2: Exercise and health
Weak: Is exercise good for health?
Why it's weak: "Exercise" is undefined (type? intensity? duration?). "Good for health" is undefined (which health outcome?). The question can be answered yes by any of dozens of review articles and doesn't require new investigation.
Strong: Among adults aged 65 and older with type 2 diabetes, does twelve weeks of supervised resistance training, three sessions per week, reduce HbA1c at 12 weeks and 6 months post-intervention compared to standard care alone?
Why it's strong: Population is defined. Intervention is operationalized in dose and duration. Comparison is specified. Outcome and time frame are clear. The question implies a specific study design (RCT).
Example 3: Education and outcomes
Weak: Does education matter?
Why it's weak: "Education" and "matter" are both vague. "Matter for what" is unspecified. There's no population, no relationship to test, and no outcome.
Strong: Does each additional year of post-secondary education increase lifetime earnings among US workers aged 25 to 64, after controlling for cognitive ability, family background, and field of study?
Why it's strong: Variable is specified (years of post-secondary education). Outcome is specified (lifetime earnings). Population is defined. Confounders are addressed. The question implies a specific analytical approach (regression with controls).
Example 4: Climate and ecosystems
Weak: How does climate change affect nature?
Why it's weak: "Climate change" needs operationalization (which aspect: temperature, precipitation, extremes?). "Nature" is undefined. "Affect" specifies no direction or mechanism.
Strong: What is the relationship between sea surface temperature anomalies in the eastern equatorial Pacific and winter precipitation in the southwestern United States, based on historical records from 1950 to 2024?
Why it's strong: Both variables are specified. Geographic scope is defined. Time frame is set. The question implies time-series analysis.
Example 5: Literature and culture
Weak: What do Appalachian books say about Appalachia?
Why it's weak: The corpus is undefined. "Say about" is too open. There's no analytic framework specified.
Strong: How do Appalachian women writers from 1970 to 2010 represent the relationship between place and identity in their fiction, and how do these representations change across the period in response to the region's economic transitions?
Why it's strong: The corpus is bounded (Appalachian women writers, 1970 to 2010). The analytic focus is specified (place and identity, with attention to economic context). The temporal frame allows for change-over-time analysis.
Example 6: Workplace and well-being
Weak: Is remote work good for employees?
Why it's weak: "Remote work" doesn't specify configuration (fully remote? hybrid? what proportion?). "Good for employees" is undefined (productivity? wellbeing? retention? compensation?).
Strong: Among knowledge workers at large US technology companies, does a hybrid work arrangement (two days remote per week) compared to fully in-office work affect self-reported job satisfaction, productivity as measured by self-reported output, and turnover intention, in a panel survey conducted at three points across one year?
Why it's strong: Population is specified. The work arrangement is operationalized. Multiple outcomes are specified with measures. Time frame is set.
How to Develop Your Own Research Question
Use the examples above as models. Identify the example closest to your topic and methodological approach, then adapt the structure: define your population, specify your variables, identify your comparison, and operationalize your outcome. Most research questions go through five to ten drafts before they're submission-ready, and that's normal. For full step-by-step guidance on developing your own research question from a broad topic, including the FINER, PICO, PICOT, and SPIDER frameworks and detailed treatment of common mistakes, see our companion article on how to write a research question.
From Research Question to Research Manuscript
Once you have a strong research question, the rest of the research process flows from it: study design follows the question, data collection and analysis follow the design, and the manuscript reports what you found. The writing matters too. A strong study with weak writing often gets desk-rejected before reviewers consider the substance.
Editor World's academic editing service works with researchers from initial draft through journal submission. Our editors hold advanced degrees across the social sciences, the natural and physical sciences, medicine, engineering, computer science, and the humanities, and you select your editor by subject matter expertise before submitting. Editors average 15 years of professional experience and have edited manuscripts that have appeared in top-tier journals across disciplines. Our journal article editing service focuses specifically on preparing manuscripts to the standard international peer reviewers expect, and our dissertation editing service reviews full-length doctoral and master's theses as a unit. Every document is reviewed entirely by a qualified native English editor; no AI tools are used at any stage. A certificate of editing is available as an optional add-on for any manuscript.
For specific guidance on related stages of the research process, see our articles on how to write a research question, how to outline an essay, how to improve essay writing, ideal paragraph length and structure, and what to do after journal rejection. For ESL researchers, our article on common English writing mistakes non-native speakers make covers the patterns that most often affect manuscript clarity.
Frequently Asked Questions
What is a good example of a research question?
A good example of a research question is one that specifies the population, the relationship being tested, and the outcome being measured, while remaining feasible and complex enough to merit investigation. For example: "Among adults aged 65 and older with type 2 diabetes, does twelve weeks of supervised resistance training compared to standard care alone reduce HbA1c at 12 weeks and 6 months post-intervention?" This question identifies the population (older adults with type 2 diabetes), the intervention (specified resistance training program), the comparison (standard care), the outcome (HbA1c), and the time frame (12 weeks and 6 months). It implies a randomized controlled trial design and produces a measurable answer. By contrast, a weak version of the same question would be: "Is exercise good for diabetes?" That version is unanswerable because exercise type, dose, and duration are unspecified, the outcome is undefined, the population is too broad, and the question can be answered yes from any review article. Strong research questions across all disciplines share this pattern: specific population, operationalized variables, defined outcome, and bounded conditions.
What are the five types of research questions?
Research questions are commonly grouped into five types based on what they ask. Descriptive questions ask what something is or how it's distributed (for example: "What proportion of US adults aged 18 to 64 received a diagnosis of major depressive disorder in 2024?"). Comparative questions ask whether two or more groups differ on some outcome (for example: "How does the four-year graduation rate of first-generation college students differ from continuing-generation students at large public universities?"). Correlational questions ask whether two variables are associated, without claiming causation (for example: "What is the relationship between household financial literacy and retirement savings adequacy among US households aged 45 to 64?"). Causal or explanatory questions ask whether one variable causes another (for example: "Does universal pre-K enrollment increase third-grade reading proficiency among children from low-income households?"). Predictive questions ask what will happen under specified conditions (for example: "Based on current emission trends, what will be the average global temperature increase by 2100?"). Some taxonomies add exploratory, evaluative, and theoretical questions, but the five-type taxonomy covers most empirical research.
What are examples of research questions in the health sciences?
Strong research questions in the health sciences typically follow the PICO or PICOT framework, specifying Population, Intervention, Comparison, Outcome, and (in PICOT) Time. Examples include: "Among adults aged 65 and older with type 2 diabetes, does twelve weeks of supervised resistance training compared to standard care alone reduce HbA1c at 12 weeks and 6 months post-intervention?" "Among patients with stage III colon cancer following surgical resection, does adding an immune checkpoint inhibitor to standard FOLFOX chemotherapy improve five-year overall survival compared to FOLFOX alone?" "Among pregnant women in the third trimester with gestational hypertension, does daily low-dose aspirin compared to placebo reduce the incidence of preeclampsia through delivery?" "What is the dose-response relationship between weekly minutes of moderate-to-vigorous physical activity and all-cause mortality among US adults aged 40 and older, after adjusting for age, sex, BMI, and baseline health status?" Each example specifies who is being studied, what is being done or measured, what the comparison is, what outcome is being assessed, and over what time frame.
What are examples of qualitative research questions?
Qualitative research questions ask about experiences, meanings, processes, and contexts, using language like "how do," "what is the experience of," "how do participants describe," and "in what ways." Examples include: "How do first-generation college students at large public research universities describe their experience of belonging on campus during their first year?" "What are the lived experiences of registered nurses providing end-of-life care in pediatric intensive care units, and how do they describe the supports they need?" "How do family caregivers of older adults with advanced dementia describe their changing roles and identities over the course of providing care?" "How do small business owners in underserved Appalachian communities in western Pennsylvania describe the barriers and supports they encounter in accessing capital?" Qualitative questions imply interview, focus group, observation, or document analysis methods rather than statistical analysis, and they produce rich descriptions, theoretical insights, and conceptual frameworks rather than numerical estimates.
What is an example of a PICO research question?
A PICO research question makes the Population, Intervention, Comparison, and Outcome explicit. PICOT adds Time as a fifth element. An example PICOT question is: "Among adults aged 65 and older with type 2 diabetes (Population), does twelve weeks of supervised resistance training, three sessions per week (Intervention), compared to standard care alone (Comparison), reduce HbA1c (Outcome) at 12 weeks and 6 months post-intervention (Time)?" Each component is specified. Population identifies who is being studied with relevant characteristics. Intervention specifies the treatment with dose, duration, and form. Comparison specifies the alternative being tested against. Outcome specifies the measurable result with its construct and measure. Time specifies the period over which the outcome is assessed. PICO and PICOT are most useful for quantitative clinical research with well-defined interventions and outcomes, and they're the standard structure for evidence-based practice questions in medicine, nursing, and public health.
What is an example of a research question in education?
Strong research questions in education specify the population, the educational variable or intervention, the outcome, and the conditions. Examples include: "Does universal pre-K enrollment increase third-grade reading proficiency among children from low-income households, as measured by state standardized assessments, compared to children who did not attend pre-K, in school districts that adopted universal pre-K between 2018 and 2022?" "Does the use of intelligent tutoring systems in middle school algebra produce greater learning gains than teacher-led instruction alone, as measured by end-of-year algebra assessments, in a randomized trial across 50 US middle schools?" "How does the four-year graduation rate of first-generation college students differ from continuing-generation students at large public research universities, after controlling for high school GPA, SAT/ACT scores, and high school socioeconomic status?" Qualitative education questions might include: "How do new teachers in their first three years describe the gap between their teacher preparation programs and the realities of their classrooms, and what supports do they identify as most useful in bridging that gap?"
How do I write my own research question using these examples?
To use the examples in this article as models for your own research question, follow four steps. First, find the example closest to your topic and methodological approach. If you're doing quantitative work in the social sciences, look at the social sciences quantitative examples. If you're doing qualitative work in nursing, look at the qualitative health sciences examples. Second, identify the structural pattern of that example: which population is specified, which variables are operationalized, which comparison is made, which outcome is measured, and over what time frame. Third, adapt the same pattern to your own topic by replacing the example's population, variables, and outcome with yours. Fourth, test your draft question against the FINER criteria (Feasible, Interesting, Novel, Ethical, Relevant) and revise. Most research questions go through five to ten drafts before they're submission-ready. For full step-by-step guidance including the eight-step process for developing a research question from a broad topic and the major frameworks (FINER, PICO, PICOT, SPIDER, PEO), see our companion article on how to write a research question.
What makes a research question weak?
Seven characteristics make a research question weak. First, the question is too broad, more like a topic description than a research question ("How does social media affect mental health?"). Second, the question is too narrow, asking about a single individual or moment ("Did Mary Smith experience improved mood after using a meditation app for two weeks in March 2024?"). Third, the question is yes/no answerable from existing reviews ("Is exercise good for health?"). Fourth, the question contains undefined or vague terms like "technology," "well-being," "factors," or "affects," that can mean radically different things in different studies. Fifth, the question assumes the answer rather than asking the relationship as a question ("How does social media damage adolescent mental health?" assumes the conclusion). Sixth, the question isn't researchable with available methods, requiring data or analysis that nobody can produce. Seventh, the question doesn't connect to existing literature, suggesting the writer skipped preliminary reading. Each weakness has a specific fix: narrow, broaden, complicate, define, neutralize, reframe, or read more.
What is an example of a research question for a dissertation?
Dissertation research questions should be sophisticated enough to merit four to six years of doctoral training and should make a clear contribution to the field. Many dissertations now use the three-paper format, where each paper has its own research question. An example three-paper dissertation in household financial decision-making might include: Paper 1: Are there gender differences in financial risk tolerance among married US couples, controlling for income, education, and age? Paper 2: Do gender differences in risk tolerance translate into differences in household investment portfolio allocations, using linked spousal survey data? Paper 3: How do married couples describe the process of making joint financial decisions, and how do gendered differences in stated risk tolerance manifest in actual joint decision-making conversations? Alternatively, a single-question dissertation might ask: "Does universal pre-K enrollment increase third-grade reading proficiency, fourth-grade math proficiency, and high school graduation rates among children from low-income households, in school districts that adopted universal pre-K between 2010 and 2015, with effects estimated through a difference-in-differences design?" Doctoral questions are more demanding than master's questions in scope, sophistication, and originality.
What is an example of a research question for a grant application?
Grant applications, including NIH R01s, NSF proposals, and ERC grants, typically include specific aims that function as research questions. The aims should collectively justify the funding requested and demonstrate that the research team can answer them. An example NIH R01 on cardiovascular health might have three aims: Aim 1: Determine whether long-term exposure to fine particulate matter increases the incidence of myocardial infarction in a cohort of 50,000 US adults aged 45 to 75, followed for 10 years, after adjustment for known cardiovascular risk factors. Aim 2: Identify the molecular mechanisms by which PM2.5 exposure promotes atherosclerotic plaque instability, using ApoE-knockout mouse models. Aim 3: Test whether a community-level air quality intervention reduces inflammatory biomarker levels among adults living within one mile of major freeways, using a stepped-wedge design across six study sites. Each aim functions as a research question, the aims collectively justify the budget and timeline requested, and the proposed methods demonstrate the team's ability to answer the questions. Strong grant aims are framed as testable questions with clear hypotheses, defined methods, and measurable outcomes.
How many research questions should a study have?
A typical research project has one main research question, sometimes with two to four sub-questions that break the main question into testable components. Undergraduate research papers usually have a single research question. Master's theses typically have one main question, possibly with two or three sub-questions. Doctoral dissertations may have one main question with multiple sub-questions, or may consist of three or four related studies in the three-paper format, each with its own research question. Grant applications typically have two to four specific aims that function as research questions and collectively justify the funding requested. Journal articles typically address one research question or one closely related set of questions. The total number of questions matters less than whether they cohere around a central problem and whether each can be answered within the resources of the project. As a rule of thumb, more than five sub-questions for a single thesis or dissertation suggests the main question isn't specific enough or that the project is trying to do too much.
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